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. 2020 Nov 9;12(11):3309. doi: 10.3390/cancers12113309

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Analysis of overall survival of the #1 and #2 mucin signatures in pancreatic cancer datasets using SurvExpress. (A) Hazard ratio according to signature #1 (MUC1, MUC4, MUC16, MUC17, MUC20, and MUC21) and #2 (MUC14/EMCN, MUC15, and MUC18) high and low expression in the pancreatic adenocarcinoma PAAD cohort. (B) PAAD patients were stratified using a gene signature combining MUC1, MUC4, MUC16, MUC17, MUC20, and MUC21. Kaplan–Meier curves were analyzed using the optimized SurvExpress Maximize algorithm. The number of analyzed patients across time (days) is indicated below the horizontal axis for both conditions. (C) PAAD patients were stratified using a gene signature combining MUC15, MUC14/EMCN, and MUC18/MCAM using the Maximize algorithm.