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Time-course of changes in (A) total protein (mg/L), (B) albumin (mg/L), (C) globulin (mg/l) and (D) albumin-to-globulin ratio (A/G) over three weeks of complete decongestive therapy (CDT) and due to manual lymphatic drainage (MLD). The blue circles represent values pre-MLD, the red boxes indicate fluid concentrations post-MLD. Asterisks (*) indicate significant changes in albumin (p = 0.005) and A/G ratio (p = 0.049) pre-compared to post-MLD.
