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Percentage of advanced stage disc degeneration at different intervertebral disc (IVD) levels. The degree of disc degeneration was evaluated by sagittal T2-weighted lumbar magnetic resonance imaging (MRI) and was graded according to Pfirrmann’s classification [14] from Grades I to V. Grades I, II and III were defined as early stage IVD degeneration and Grades IV and V as advanced stage
