Individuals with at least three or more affected relatives, of whom at least one is an FDR to the individual considered for screening |
Individuals with at least two affected relatives who are FDRs to each other, of whom at least one is an FDR to the individual considered for surveillance |
Individuals with at least two affected relatives on the same side of the family, of whom at least one is an FDR to the individual considered for surveillance |
LKB1/STK11 mutation carriers (PJS) regardless of family history |
CDKN2A mutation carriers regardless of family history |
BRCA1 mutation carriers with one affected FDR |
BRCA2 mutation carriers with one affected FDR (or two affected family members, no FDR) with PC |
PALB2 mutation carriers with one affected FDR |
MMR gene mutation carriers (LS) with one affected FDR |
ATM mutation carriers with one affected FDR |