Table 2.
BoNT concentration (mouse lethal dose (MLD)/mL) in the sera of patients with food-borne botulism.
| Country | Year | Number of Patient’s Sera | Days from Symptom Onset to Serum Sampling | BoNT Type | BoNT Concentration (MLD/mL) | References |
|---|---|---|---|---|---|---|
| USA | 1963 | 5 | 1–10 | E | 1–10 | [44] |
| France 1 | 1970–1973 | 1 | 120 | B | 1 | [43] |
| 17 | 3–20 (most 8–15) | B | 1–10 | |||
| 1 | 21 | B | 4–40 | |||
| Japan | 1984 | 1 | 4 | B | 1–2 | [54] |
| Finland | 1997 | 1 | E | 6 | [58] | |
| Finland | 1999 | 1 | 1 | E | 1 | [60] |
| Turkey | 2005 | 9 | A | <1–2 | [67] | |
| USA | 2006 | 1 (patient A) | 1 | A | >20 | [68] |
| 1 (patient B) | 5 | A | >200 | |||
| 7 | 1800 | |||||
| 8 | >200 | |||||
| 12 | >200 | |||||
| France | 2007–2016 | 1 | A | 80 | [47,48,49] | |
| 2 | A | 32–40 | ||||
| 2 | A | 8–16 | ||||
| 35 | A | 1–8 | ||||
| 6 | B | 16–40 | ||||
| 67 | B | 1–8 | ||||
| 14 | B | <1 | ||||
| 1 | E | 8 | ||||
| 2 | E | 1 | ||||
| Finland | 2011 | 1 | 3 | B | <1 | [74] |
| France | 2014 | 1 | 2 | F (C. baratii) | 400 | [84,85] |
| 1 | 2 | 1–2 | ||||
| France | 2015 | 3 | F (C. baratii) | 1-4 | [85] |
1 BoNT concentration determined in 19 sera of 28 toxin positive sera.