Table 2.

The role of CCL chemokines in gastric cancer (GC)

Chemokines/Receptors of Chemokines	Source	Results	References
CCL2	Expression	Elevated in 66% of GC specimen, correlated with lower overall survival rate	[33]
	Plasma concentration	Correlated with clinical stage of GC	[10]
CCL5	Serum concentration	Higher in GC than control group, overall survival reduced when elevated, elevated concentration correlated with more advanced stage of the tumor, higher depth invasion, low histological differentiation and lymph node involvement	[30]
		Increased concentration correlated with higher T-stage, N-stage, peritoneal metastasis and decreased survival	[31]
CCL10	Plasma concentration	Correlated with clinical stage of GC	[10]

T-stage—depth of tumor invasion. N-stage—presence of lymph node metastasis.