Figure 4.
Binding of raft RNA aptamers to lipid raft regions of plasma membrane of neuroblastoma IMR-32 cells by fluorescence and FRET microscopy (representative confocal fluorescent images of IMR-32 cells): green (column I)—YOYO-1 bound to raft RNA aptamers; red (column II)—AlexaFluor-555 conjugated to cholera toxin B (CTB555) bound to the ganglioside GM1 within lipid raft region of the plasma membrane; column III—merged images; column IV—FRET signal. The bars represent 3.15 μm. (A,B) stand for two independent experiments.