Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Functionalization scheme of GO/PSi hybrid device with the PNA probe and hybridization with the DNA target. Reaction 1: hydrosilylation of PSi by UDA (18 h at 110 °C). Reaction 2: PEGylation of PSi by EDC/NHS chemistry and deprotection of NH-BOC group by TFA treatment. Reaction 3: GO conjugation to PEGylated-PSi by EDC/NHS. Reaction 4: immobilization of the PNA by a covalent chemistry. Reaction 5: DNA target recognition by hybridization.
