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IHC of the co-expression of ASCL1 and three key molecules in SCLC samples: Serial section immunostaining for ASCL1 (A) and NEUROD1 (B). SCLC cell nuclei were positive for ASCL1 (A) and NEUROD1 (B). Serial section immunostaining for ASCL1 (C) and YAP1 (D). SCLC cell nuclei were positive for ASCL1 (C), and the cytoplasm was positive for YAP1 (D). SCLC cell nuclei were positive for ASCL1 (E), and the cytoplasm was positive for POU2F3 (F). Scale bar = 100 μm.
