Table 2.
Immunohistochemical results in SCLC.
| Antibody | Positive Rate (%) | Expression Level | ||
|---|---|---|---|---|
| Low | Medium | High | ||
| ASCL1 | 72.3 | 17.6 | 67.6 | 14.7 |
| NEUROD1 | 10.6 | 80.0 | 20.0 | 0 |
| YAP1 | 14.9 | 57.1 | 42.9 | 0 |
| POU2F3 | 38.4 | 66.7 | 20.0 | 13.3 |
| CGA | 74.5 | 34.2 | 28.6 | 37.1 |
| SYP | 87.0 | 7.5 | 35.0 | 57.5 |
| NCAM | 91.3 | 14.3 | 42.9 | 42.9 |
| INSM1 | 83.0 | 12.8 | 33.3 | 53.8 |
| NOTCH1 | 17.4 | 75.0 | 12.5 | 12.5 |
| NOTCH2 | 53.2 | 32.0 | 68.0 | 0 |
| NOTCH3 | 66.0 | 19.4 | 51.6 | 29.0 |
| SOX2 | 89.4 | 33.3 | 45.2 | 21.4 |
| SOX9 | 89.4 | 26.2 | 35.7 | 38.1 |
| E-CADHERIN | 80.9 | 39.5 | 42.1 | 18.4 |
| VIMENTIN | 6.4 | 0 | 100 | 0 |
| TTF1 | 74.5 | 2.9 | 42.9 | 54.3 |
| FGFR1 | 19.6 | 55.6 | 22.2 | 22.2 |
| MYC | 2.1 | 100 | 0 | 0 |
| E2F1 | 11.1 | 60.0 | 40.0 | 0 |
| E2F7 | 100 | 4.3 | 27.7 | 68.1 |
| BCL2 | 78.7 | 24.5 | 40.5 | 35.1 |
| PDL1 | 40.4 | 36.8 | 36.8 | 26.3 |
| EZH2 | 85.1 | 30.0 | 60.0 | 10.0 |
| TEAD1 | 80.0 | 47.2 | 47.2 | 5.6 |
| RB1 | 42.2 | 68.4 | 31.6 | 0 |
| P53 | 84.8 | 12.8 | 43.6 | 43.6 |
| P130 | 57.4 | 18.5 | 77.8 | 7.4 |
| DLL3 | 37.0 | 52.9 | 29.4 | 17.6 |
| HES1 | 51.1 | 8.3 | 83.8 | 8.3 |
| REST | 19.1 | 11.1 | 88.9 | 0 |