Table 3.
Mean dihydrocitrinone (HO-CIT) concentrations (µg/kg) measured in plasma and edible tissues from pigs, broilers and layers 24 h after receiving CIT contaminated feed during 3 weeks at different levels (0.1, 1, 3, 3.5 mg/kg feed, depending on species). Concentrations are given ± standard deviation. n = 8 for plasma of all groups, n = 2 for edible tissues of broilers and layers and n = 8 for edible tissues of pigs.
| Animal Species | Pig | Broiler | Layer | ||
|---|---|---|---|---|---|
| Feed CIT concentration | 1 mg/kg | 0.1 mg/kg | 3 mg/kg | 0.1 mg/kg | 3.5 mg/kg |
| Plasma | 23.16 ± 8.18 | 5.02 ± 0.05 | 14.30 ± 2.69 | 2.27 ± 0.15 | 89.02 ± 17.69 |
| Muscle | <LOQ | n.d. | 9.70 ± 2.98 | <LOQ | 6.57 ± 1.97 |
| Skin + fat | 17.75 ± 14.43 | 2.67 ± 0.58 | 80.60 ± 15.64 | <LOQ | 38.01 ± 21.15 |
| Kidney | 53.23 ± 36.73 | 23.48 ± 12.76 | 118.19 * | <LOQ | 18.64 ± 14.45 |
| Liver | 80.12 ± 12.95 | n.d. | 31.97 ± 5.49 | <LOQ | 8.27 ± 8.91 |
| Egg yolk | n.a. | <LOQ | <LOQ | <LOQ | <LOQ |
| Egg white | n.a. | <LOQ | <LOQ | <LOQ | <LOQ |
* only 1 sample could be analysed. LOQ’s in pig: 0.1 ng/mL (plasma), 1 µg/kg (back muscle); 0.5 µg/kg (liver); 5 µg/kg (kidney); 1 µg/kg (skin+fat). LOQ’s in broiler and layer: 0.1 ng/mL (plasma), 1 µg/kg (breast muscle, egg yolk); 5 µg/kg (kidney, skin+fat, egg yolk); 8 µg/kg (liver). n.a.: not applicable; n.d.: not detected.