Table 1:

Studies which used a pedicled omental flap as support for bioengineered tissue to regenerate the myocardium

First author	Year	In vivo model	Coronary artery for MI	Intervention interval after MI	N per groupa	Bioengineered cardiac tissue	Mode of tissue delivery
Kainuma et al. [20]	2015	Pig	LCA	2 weeks	11	Skeletal myoblast cell sheet	Transplantation onto MI/peri-infarct area
Kanamori et al. [21]	2006	Minipig	OM1 + 2 Distal D1	1 h	5	Autologous bone marrow-derived mononuclear cells	Injection into MI/peri-infarct area
Kawamura et al. [22]	2017	Pig	LAD	1 month	7	Human iPSC cardiomyocyte cell sheets	Transplantation onto MI area
Lilyanna et al. [23]	2013	Rat	LAD	2 weeks	11	Fibrin graft containing cord-lining mesenchymal stem cells	Transplantation onto MI area. Attached using fibrin glue
Shudo et al. [24]	2011	Minipig	LAD	4 weeks	6	Cell sheets consisting of skeletal myoblast cells	Transplantation onto MI/peri-infarct area
Suzuki et al. [25]	2009	Rat	LAD	At initial procedure	10	Myocardial cell sheets	Transplantation onto MI area
Takaba et al. [26]	2006	Rabbit	Cx	4 weeks	8	Gelatine hydrogel sheet with bFGF applied	Transplantation onto MI area
Ueyama et al. [27]	2004	Rabbit	Cx	At initial procedure	10	Gelatine hydrogel sheet with bFGF applied	Transplantation onto MI area
Yajima et al. [28]	2018	Pig	LAD	4 weeks	6	Gelatine compressed sponge immersed in ONO-13301ST (slow-releasing synthetic prostacyclin agonist)	Transplantation onto MI area
Zhang et al. [29]	2011	Rat	LCA	3 weeks	17	Autologous tissue patch from left atrial appendage	Transplantation onto MI area
Zhou et al. [30]	2010	Rat	LCA	8 weeks	16	Cell patch of polylactic acid-co-glycolic acid polymer seeded with mesenchymal stem cells	Transplantation onto MI area

^aDefined as the treatment group in which both the bioengineered cardiac tissue and greater omentum were applied.

bFGF: basic fibroblast growth factor; Cx: circumflex coronary artery; D1: first diagonal artery; iPSC: induced pluripotent stem cell; LAD: left anterior descending coronary artery; LCA: left coronary artery; MI: myocardial infarction; OM1 + 2: obtuse marginal coronary artery 1 and 2.