Table 3.
Genomic regions associated with monounsaturated fatty acids of Longissimus thoracis et lumborum muscle in rabbits.
| OCU 1 | Region (Mb) 2 | Trait | VAR 3 | PPA 4 | rSNP 5 | Number of Genes 6 | PCG 7 |
|---|---|---|---|---|---|---|---|
| 1 | 29.1–29.9 | C16:1n7 | 0.81 | 0.48 | 16 | 3 | - |
| 36.0–36.9 | C16:1n7 | 0.92 | 0.34 | 3 | 2 | - | |
| 121.0–121.9 | C18:1n9 | 0.63 | 0.34 | 2 | 13 | MTMR2 | |
| MUFA | 0.61 | 0.38 | 18 | ||||
| 3 | 149.0–149.9 | C18:1n9 | 1.06 | 0.64 | 17 | 11 | ENSOCUG00000000157 |
| MUFA | 1.38 | 0.77 | 18 | ||||
| 4 | 67.0–67.9 | C18:1n9 | 0.66 | 0.41 | 14 | 8 | - |
| 5 | 7.2–7.9 | C16:1n7 | 0.82 | 0.61 | 22 | 1 | - |
| MUFA | 0.99 | 0.64 | 22 | ||||
| 6 | 8–9.9 | C16:1n7 | 0.71 | 0.64 | 22 | 22 | SMG1, GDE1 |
| C18:1n9 | 1.43 | 0.50 | 12 | ||||
| MUFA | 0.67 | 0.47 | 10 | ||||
| 8 | 21.0–21.9 | C16:1n7 | 0.63 | 0.65 | 8 | 6 | PIK3C2G, PLCZ1, |
| C18:1n9 | 0.72 | 0.57 | 4 | PLEKHA5 | |||
| MUFA | 1.01 | 0.66 | 16 | ||||
| 9 | 12.0–12.5 | C16:1n7 | 1.05 | 0.60 | 17 | 7 | PPARG |
| 10 | 42.2–42.9 | MUFA | 0.53 | 0.41 | 16 | 1 | - |
| 13 | 126.0–126.9 | C18:1n9 | 1.28 | 0.73 | 9 | 23 | HEYL, MFSD2A, PPT1 |
| MUFA | 0.99 | 0.69 | 9 | ||||
| 14 | 82.0–82.9 | C18:1n9 | 0.58 | 0.30 | 7 | 14 | ADIPOQ |
| 17 | 12.0–13.9 | C16:1n7 | 1.55 | 0.66 | 35 | 14 | ALDH1A2, LIPC, MYO1E |
| MUFA | 0.81 | 0.56 | 36 | ||||
| 18 | 47.0–48.9 | C16:1n7 | 1.21 | 0.43 | 7 | 35 | GOT1, ERLIN1, |
| C18:1n9 | 0.83 | 0.37 | 2 | ENSOCUG00000014801, | |||
| MUFA | 1.90 | 0.53 | 46 | ENSOCUG00000001375 | |||
| 21 | 10.0–10.9 | C18:1n9 | 0.72 | 0.44 | 6 | 2 | - |
1 Rabbit chromosome, 2 associated region, 3 percentage of the genomic variance explained by the windows belonging to the associated region, 4 posterior probability of association, 5 number of relevant SNPs with a Bayes factor higher than 10 in the extended region, 6 number of protein coding genes in the extended region, 7 putative candidate genes related to lipid metabolism retrieved from DAVID database. MUFA: monounsaturated fatty acids stand for the sum of C16:1n7, C18:1n9, C18:1n7, C20:1n11, and C22:1n9.