IO |
Immuno-oncology |
ICI |
Immune checkpoint inhibitor |
IgG1 |
Immunoglobulin G |
CTLA-4 |
Cytotoxic T-lymphocyte antigen-4 |
TME |
Tumor microenvironment |
OV |
Oncolytic virus |
Ab |
Antibody |
PD-1 |
Programmed death 1 |
PD-L1 |
Programmed death-ligand 1 |
irAE |
Immune-related adverse events |
TIL |
Tumor infiltrating lymphocyte |
HMGB-1 |
High-mobility group protein box 1 |
TIM-3 |
T cell immunoglobulin and mucin domain 3 |
APC |
Antigen-presenting cells |
IFN- γ |
Interferon gamma |
IL-4 |
Interleukin |
DC |
Dendritic cells |
LAG-3 |
Lymphocyte-activation gene 3 |
MHC |
Major histocompatibility complex |
Treg |
Regulatory T cells |
RGBM |
Recurrent glioblastoma |
Gal-9 |
Galectin-9 |
CEACAM1 |
Carcinoembryonic antigen-related cell adhesion molecule 1 |
PS |
Phosphatidylserine |
TIGIT |
Tyrosine-based inhibition motif domain |
VISTA |
V-domain Ig suppressor of T cell activation |
PAMPS |
Pathogen-associated molecular patterns |
TAA |
Tumor-associated antigens |
DAMPS |
Danger-associated molecular patterns |
IL-12 |
Interleukin 12 |
GM-CSF |
Granulocyte-macrophage colony-stimulating factor |
HSV |
Herpes simplex virus |
MAGE-A3 |
Melanoma-associated antigen 3 |
NY-ESO-1 |
New York esophageal squamous cell carcinoma 1 |
TNF-α |
Tumor necrosis factor-alpha |
IL-2 |
Interleukin 2 |
hTERT |
Human telomerase reverse transcriptase |
MART |
T cell-recognized melanoma antigen |
DLT |
Dose-limiting toxicity |
ICAM |
Intercellular adhesion molecule 1 |
DAF |
Decay-accelerating factor |
NIS |
Sodium iodide symporter |
NSCLS |
Non-small-cell lung carcinoma |
AML |
Acute myeloid leukemia |
TNBC |
Triple negative breast cancer |
IRES |
Internal ribosome entry site |
NDV |
Newcastle disease virus |
ICOS |
Inducible co-stimulator |