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(a) A. fumigatus MAPK mutant showing tolerance to the repurposed benzoic ingredient (Kim et al., unpublished observation); (b) scheme describing structural modifications of cinnamates or benzoates that could overcome the tolerance of S. cerevisiae glr1Δ or A. fumigatus MAPK mutants, respectively, to the repurposed compounds (see Figure 1 and [243] for cinnamates).
