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. 2020 Nov 15;9(11):1134. doi: 10.3390/antiox9111134

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Mesangial matrix and quantitative analysis of rat kidneys. Representative photomicrographs of one kidney cortex section of each experimental group. Control (Ctrl) with no changes in glomeruli mesangium seen in light purple (arrows). Diabetes (DM) illustrates expansion of the mesangium (arrows), which is thicker and denser than the one of control group. Diabetes + Allicin (DA) depicts a mesangium (arrows) with characteristics between the control and the DM groups. Periodic acid-Schiff (PAS stain), 200× original magnification. Graph shows quantitative analysis of mesangial matrix index. Values are expressed as mean ± SEM of n = 5 * p < 0.001 vs. Ctrl; ⁺ p < 0.001 vs. DM.