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Differential gene expressions of the five microRNAs targeting the toll-like receptor pathway in response to Mycobacterium TB-specific antigen stimuli in vitro. In vitro ESAT6, CFP10, and lipopolysaccharide (LPS) stimuli in THP-1 cells resulted in down-regulations of (a) miR-23a-3p and (b) miR-155-5p, and up-regulations of (c) miR-146a-5p, (d) TLR4, (e) TLR2, and (f) tumor necrosis factor (TNF)-α. § p < 0.05, compared with normal control (NC; culture medium) by Kruskal–Wallis H test.
