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. 2020 Nov 10;9(11):1106. doi: 10.3390/antiox9111106

Figure 4.

Figure 4

Hypopigmenting activity of methionine-histidine-isoleucine-arginine-leucine (MHIRL) family peptides in melanocytes. The effects of MHIRL family on cell viability (a) in Mel-Ab cells and (b) in B16F10 cells. [peptide] = 100 μM. The melanogenesis inhibitory activities of the MHIRL family (c) in Mel-Ab cells and (d) in B16F10 cells. [peptide] = 100 μM. The melanogenesis inhibitory activities of MHIR (e) in Mel-Ab cells and (f) in B16F10 cells. (g) Remaining melanin contents (%) in α-MSH treated B16F10 cells with N-terminal acetylated MHIR (Ac-MHIR) at various concentrations. Each experiment was carried out in triplicate and the values are presented as the mean ± standard error.