Table 6.
Changes in intensity of the main symptoms between day 0 and day 7 according to the setting of care in 508 patients overall and in those symptomatic at baseline.
| Symptoms | Setting | All Patients | Symptomatic Patients | ||||
|---|---|---|---|---|---|---|---|
| Intensity a, Mean (SD) | Intensity a, Mean (SD) | ||||||
| Day 0 | Day 7 | p Value b | Day 0 | Day 7 | p Value b | ||
| Asthenia | Home | 4.81 (2.59) | 4.57 (2.48) | <0.05 | 5.15 (2.34) | 4.80 (2.34) | <0.01 |
| Hospice | 5.12 (2.52) | 4.16 (2.45) | <0.01 | 5.54 (2.12) | 4.33 (2.40) | <0.001 | |
| Hospital | 5.00 (2.74) | 4.25 (2.98) | NS | 5.64 (2.18) | 4.08 (2.85) | <0.01 | |
| p value c | NS | NS | NS | NS | |||
| Poor well-being | Home | 3.99 (2.79) | 3.70 (2.70) | <0.01 | 4.92 (2.24) | 4.35 (2.46) | <0.001 |
| Hospice | 3.28 (3.01) | 2.84 (2.68) | NS | 4.79 (2.44) | 3.37 (2.68) | <0.001 | |
| Hospital | 3.34 (2.88) | 2.66 (2.45) | NS | 4.74 (2.25) | 2.90 (2.45) | <0.001 | |
| p value c | <0.05 | <0.01 | NS | <0.001 | |||
| Lack of appetite | Home | 3.65 (3.00) | 3.30 (2.86) | <0.01 | 4.85 (2.47) | 4.06 (2.70) | <0.001 |
| Hospice | 3.99 (3.27) | 3.10 (3.19) | <0.01 | 5.40 (2.61) | 3.68 (3.09) | <0.001 | |
| Hospital | 2.50 (2.51) | 2.45 (2.86) | NS | 4.23 (1.80) | 3.31 (2.75) | NS | |
| p value c | <0.05 | NS | NS | NS | |||
| Drowsiness | Home | 2.98 (2.68) | 2.80 (2.55) | NS | 4.20 (2.23) | 3.57 (2.43) | <0.001 |
| Hospice | 3.00 (2.89) | 2.90 (2.74) | NS | 4.31 (2.51) | 3.69 (2.56) | NS | |
| Hospital | 3.09 (2.96) | 2.25 (2.71) | NS | 4.69 (2.39) | 2.55 (2.85) | <0.01 | |
| p value c | NS | NS | NS | NS | |||
| Pain | Home | 3.14 (2.63) | 2.45 (2.29) | <0.001 | 4.38 (2.06) | 3.15 (2.17) | <0.001 |
| Hospice | 2.08 (2.59) | 1.42 (2.04) | <0.01 | 4.24 (2.11) | 2.64 (2.29) | <0.001 | |
| Hospital | 3.20 (2.74) | 1.66 (2.07) | <0.001 | 4.55 (2.11) | 2.06 (2.22) | <0.001 | |
| p value c | <0.001 | <0.001 | NS | <0.01 | |||
| Depression | Home | 2.55 (2.82) | 2.63 (2.78) | NS | 4.24 (2.45) | 3.88 (2.60) | <0.05 |
| Hospice | 3.32 (3.00) | 2.89 (2.70) | NS | 4.55 (2.60) | 3.61 (2.64) | <0.05 | |
| Hospital | 1.25 (2.25) | 1.73 (2.42) | NS | 4.23 (2.13) | 3.15 (2.54) | NS | |
| p value c | <0.001 | <0.05 | NS | NS | |||
| Anxiety | Home | 2.22 (2.61) | 2.43 (2.65) | NS | 3.95 (2.30) | 3.55 (2.50) | <0.05 |
| Hospice | 2.47 (2.80) | 2.04 (2.53) | NS | 4.05 (2.53) | 2.71 (2.74) | <0.001 | |
| Hospital | 2.32 (2.52) | 1.34 (1.57) | <0.05 | 4.08 (1.98) | 1.64 (1.66) | <0.001 | |
| p value b | NS | <0.05 | NS | <0.001 | |||
| Breathlessness | Home | 1.97 (2.65) | 1.64 (2.50) | <0.001 | 4.02 (2.48) | 3.15 (2.72) | <0.001 |
| Hospice | 1.75 (2.69) | 1.38 (2.51) | NS | 4.47 (2.51) | 3.25 (3.17) | <0.05 | |
| Hospital | 1.86 (3.01) | 1.23 (2.41) | NS | 5.47 (2.59) | 2.87 (3.42) | <0.05 | |
| p value c | NS | NS | NS | NS | |||
| Nausea | Home | 1.86 (2.45) | 1.59 (2.28) | <0.01 | 3.70 (2.26) | 2.82 (2.46) | <0.001 |
| Hospice | 1.05 (2.02) | 0.51 (1.43) | <0.001 | 3.23 (2.36) | 1.17 (1.84) | <0.001 | |
| Hospital | 0.66 (1.67) | 0.32 (0.83) | NS | 3.62 (2.20) | 0.62 (1.41) | <0.05 | |
| p value c | <0.001 | <0.001 | NS | NS | |||
NS, not statistically significant; SD, standard deviation. a Measured using a numeric rating scale from 0 to 10; b p value for difference between day 7 and day 0; c p value for difference between care settings.