8-OHdG |
8-hydroxy-2′-deoxyguanosine |
8-oxodG |
8-oxo-7,8-dihydro-2′-deoxyguanosine |
ACF |
Aberrant crypt foci |
AMPK |
AMP-activated protein kinase |
AOM |
Azoxymethane |
APC |
Adenomatous polyposis coli |
AR |
Aldose reductase |
ARE |
Antioxidant responsive element |
αSMA |
α-smooth muscle actin |
ATG4 |
Autophagy related 4A cysteine peptidase |
ATP |
Adenosine triphosphate |
Bcl-2 |
B-cell lymphoma 2 |
BER |
Base excision repair |
CAFs |
Cancer-associated fibroblasts |
CD |
Crohn’s disease |
COX-2 |
Cyclooxygenase – 2 |
CRC |
Colorectal cancer |
CSC |
Cancer stem cells |
dG |
Deoxyguanosine |
dGTP |
Deoxyguanosine triphosphate |
DR |
Death receptor |
DUOX |
Dual oxidase |
EGFR |
Epidermal growth factor receptor |
EMT |
Epithelial–mesenchymal transition |
ER |
Endoplasmic reticulum |
ERK |
Extracellular signal-regulated kinase |
ETC |
Electron transport chain |
FAP |
Fibroblast activation protein |
FGFR4 |
Fibroblast growth factor receptor 4 |
FLIP |
Flice inhibitory protein |
GIT |
Gastrointestinal tract |
GPx |
Glutathione peroxidase |
HDAC |
Histone deacetylase |
HDACIs |
Histone deacetylase inhibitors |
HIF-1α |
Hypoxia inducible factor 1 alpha subunit |
HNE |
4-hydroxy-2-nonenal |
IBD |
Inflammatory bowel diseases |
JAK |
Janus kinases |
JNK |
c-Jun NH(2)-terminal kinase |
Keap1 |
Kelch-like ECH-associated protein 1 |
LCN-2 |
Lipocalin-2 |
LN |
Lymphoid nodules |
MAPK |
Mitogen-activated protein kinase |
MDA |
Malondialdehyde |
MDSC |
Myeloid-derived suppressor cells |
MMP |
Matrix metalloproteinase |
MMR |
Mismatch repair |
MTHFD2 |
Methylenetetrahydrofolate dehydrogenase |
MYH |
MutY homologue |
NAC |
N-acetyl-l-cysteine |
NADPH |
Nicotinamide adenine dinucleotide phosphate |
NEMO |
Nuclear factor-kappa B essential modulator |
NER |
Nucleotide excision repair |
NF-κB |
Nuclear factor kappa-light-chain-enhancer of activated B cells |
NOD/SCID |
Non-obese diabetic/Severe combined immunodeficient |
NO-NSAIDs |
Nitric oxide-releasing non-steroidal anti-inflammatory drugs |
NOS |
Nitric oxide synthase |
NOX |
Nicotinamide adenine dinucleotide phosphate oxidase |
NOXA1 |
NOX Activator 1 |
NOXO1 |
NOX Organizer 1 |
Nrf2 |
Nuclear factor erythroid 2–related factor 2 |
NRX |
Nucleoredoxin |
OGG1 |
8-oxoguanine DNA glycosylase 1 |
PDGF |
Platelet-derived growth factor |
PDT |
Photodynamic therapy |
PG |
Prostaglandin |
PHD |
Prolyl hydroxylase |
PI3K |
Phosphatidylinositol 3-kinase |
PKC |
Protein kinase C |
PMA |
Phorbol 12-myristate 13-acetate |
PPP |
Pentose phosphate pathway |
PS |
Pterostilbene |
PTEN |
Phosphatase and tensin homolog |
PTP |
Protein tyrosine phosphatase |
PUFAs |
Polyunsaturated fatty acids |
RIP |
Receptor interacting protein |
RNS |
Reactive nitrogen species |
ROS |
Reactive oxygen species |
RTK |
Receptor tyrosine kinase |
SNPs |
Single-nucleotide polymorphisms |
SOD |
Superoxide dismutase |
Sp |
Specificity protein |
STAT |
Signal transducer and activator of transcription proteins |
TAK1 |
TGF-β1-TGF-β-activated kinase 1 |
TAMs |
Tumor-associated Macrophages |
TGF-β |
Transforming growth factor beta |
TIGAR |
TP53-induced glycolysis and apoptosis regulator |
TME |
Tumor microenvironment |
TRAIL |
TNF-related apoptosis-inducing ligand |
Tregs |
Regulatory T cells |
UC |
Ulcerative colitis |
uPA |
Urokinase-type plasminogen activator |
VEGF |
Vascular endothelial growth factor |
VPS34 |
Vacuolar protein sorting 34 |
Wnt |
Wingless-related integration site |
XIAP |
X-linked inhibitor of apoptosis protein |
ZEB |
Zinc finger-E-box-binding |