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. 2020 Nov 12;21(22):8504. doi: 10.3390/ijms21228504

Table 1.

Function of CDK20 and p21Cip1/Waf1 in cancer cell line/system.

Cancer Type CDK20 p21Cip1/Waf1
Ovarian cell proliferation [59] cell survival [65]
Glioblastoma cell proliferation [36] cell proliferation [66]
Cervical carcinoma cell proliferation [23] High expression function unclear [67]
Osteosarcoma cell proliferation [60] Tumor suppressor [68]
Colorectal carcinoma cell proliferation [60] Tumor suppressor [69]
Lung cancer Oncogene [70] Tumor suppressor [71]
Head and neck cancer N/A Tumor suppressor [72]
Breast cancer Oncogene [16] Cell proliferation [73]
Liver cancer Oncogene [74] Tumor suppressor [75]