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. 2020 Nov 9;9(11):1103. doi: 10.3390/antiox9111103

Figure 5.

Figure 5

The increase of 4-HNE level cause carbonylation of mitochondrial proteins. High 4-HNE levels induced carbonylation of mitochondrial proteins either 14 days (A) and 21 days (B) post injury in CCI-only rats. Subcutaneous infusion of BPF (50 mg/kg), concurrently with surgery (day 0), prevented mitochondrial proteins carbonylation. In these conditions, prohibitin expression appeared statistically the same among groups. Gels are representative of results from 6 animals. Densitometric analyses of all animals per groups are reported. Results are expressed as mean ± SEM for 6 rats. * p < 0.05 compared to sham; † p < 0.05 compared to vehicle + CCI.