Figure 5.

The A2780/S and A2780/CP cells were pretreated with NAC (5 mM) for 1 h, followed by H₂O₂ (10 μM) for 48 h. SIRT2 and apoptosis-related proteins were detected by Western blotting (A). The A2780/S and A2780/CP cells were pretreated with NAC (5 mM) for 1 h, followed by cisplatin (2 μM) for 48 h. SIRT2 and apoptosis-related proteins were detected by Western blotting (B). Results are shown as mean ± SEM (* p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001).