Table 2.

Comparison of amino acid motifs in human PS and the T. cruzi orthologue.

TMD	T. cruzi PS-Like	aa Position *	Human PS	AA Position *
1st	WSVLN	34–38	ATIKS	98–102
2nd	SIVNALILVA	70–79	SILNAAIMIS	132–141
2nd	MV	88–89	MV	93–94
5th	SVIVG	168–172	SALMA	230–234
6th	YD	193–194	YD	256–257
6th	MV	195–196	MV	298–299
-	NSSND	256–260	AQRDS	342–346
-	-	-	SSILA	366–370
7th	PFKLGLGD	283–290	GVKLGLGD	378–385
7th	SVLSARAAL	295–303	SVLVGKASA	390–398
8th	ASTVAVCFG	312–320	ACFVAILIG	409–417
9th	PALP	339–342	PALP	433–436
9th	ALPALPISICFG	336–347	ALPALPISITFG	431–442

* Amino acid position in PS primary structure; Grey highlight denotes amino acids differences between T. cruzi and human segments.