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. 2020 Nov 17;10(11):868. doi: 10.3390/brainsci10110868

Table 1.

This table summarizes the future challenges arising from this paper.

Future Studies Surrounding the Glymphatic System and Lifestyle Choices should Aim to:

  1. Confirm the link between the glymphatic system and lifestyle choices.

  2. Replicate all glymphatic-related murine research in humans.

  3. Test easily modifiable lifestyle choices affecting glymphatic clearance in a lifestyle-based intervention in humans.

  4. Investigate whether the effects of multiple lifestyle choices on glymphatic activity cumulate or cancel each other out.

  5. Confirm that AQP4 channels are the causal pathway behind glymphatic activity.

  6. Conduct a randomized controlled trial to confirm whether lifestyle choices have an effect on glymphatic activity.

  7. Investigate the effect of Mifepristone on glymphatic activity