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. 2020 Nov 17;12(11):2716. doi: 10.3390/polym12112716

Table 2.

The correlation coefficient, rate constant, and half-life obtained by fitting the sorafenib release data into the PBS solution at pH 4.8 and pH 7.4.

Sample Saturation Release R2 Pseudo-Second- Order Rate Constant (k(mg/min)) t1/2
Pseudo- First-Order Pseudo-Second- Order Parabolic Diffusion
4.8 99.90 0.9331 0.9992 0.6387 4.32 × 10−3 134
7.4 97.96 0.8677 0.9986 0.7070 4.31 × 10−3 181