Table 1.
Cell Line | Rank | Kinase | Family | Average | KRSA | UKA |
---|---|---|---|---|---|---|
PANC1 | #1 | LCK | SRC | 96% | 91% | 100% |
PANC1 | #2 | DDR2 | DDR | 96% | 96% | |
PANC1 | #3 | LYN | SRC | 95% | 91% | 99% |
PANC1 | #4 | SRC | SRC | 92% | 91% | 92% |
PANC1 | #5 | ABL1 | ABL | 91% | 87% | 95% |
PANC1 | #6 | TEC | TEC | 90% | 100% | 80% |
PANC1 | #7 | FYN | SRC | 90% | 91% | 88% |
PANC1 | #8 | BLK | SRC | 89% | 91% | 87% |
PANC1 | #9 | TXK | TEC | 89% | 100% | 77% |
PANC1 | #10 | SRMS | SRC | 88% | 91% | 85% |
PDCL15 | #1 | DDR2 | DDR | 100% | 100% | - |
PDCL15 | #2 | LCK | SRC | 98% | 96% | 100% |
PDCL15 | #3 | LYN | SRC | 97% | 96% | 99% |
PDCL15 | #4 | TEC | TEC | 94% | 91% | 97% |
PDCL15 | #5 | SRC | SRC | 94% | 96% | 92% |
PDCL15 | #6 | FYN | SRC | 93% | 96% | 91% |
PDCL15 | #7 | PDGFRA | PDGFR | 90% | 87% | 93% |
PDCL15 | #8 | FRK | FRK | 89% | 83% | 96% |
PDCL15 | #9 | BLK | SRC | 88% | 96% | 81% |
PDCL15 | #10 | PTK7 | PTK7 | 88% | - | 88% |
PDCL5 | #1 | PTK7 | PTK7 | 99% | - | 99% |
PDCL5 | #2 | ROS1 | SEV | 97% | 100% | 95% |
PDCL5 | #3 | TNK2 | ACK | 96% | 96% | - |
PDCL5 | #4 | DDR2 | DDR | 87% | 87% | - |
PDCL5 | #5 | ALK | ALK | 86% | 74% | 97% |
PDCL5 | #6 | TXK | TEC | 83% | 65% | 100% |
PDCL5 | #7 | LTK | ALK | 80% | 74% | 86% |
PDCL5 | #8 | ITK | TEC | 79% | 65% | 93% |
PDCL5 | #9 | FLT1 | VEGFR | 78% | 91% | 65% |
PDCL5 | #10 | EPHB1 | EPH | 76% | 61% | 92% |
Patient-Derived | #1 | PTK7 | PTK7 | 100% | - | 100% |
Patient-Derived | #2 | DDR2 | DDR | 100% | 100% | - |
Patient-Derived | #3 | LYN | SRC | 96% | 96% | 96% |
Patient-Derived | #4 | TXK | TEC | 95% | 91% | 99% |
Patient-Derived | #5 | TEC | TEC | 94% | 91% | 97% |
Patient-Derived | #6 | LCK | SRC | 92% | 96% | 88% |
Patient-Derived | #7 | BLK | SRC | 91% | 96% | 87% |
Patient-Derived | #8 | SRMS | SRC | 87% | 96% | 79% |
Patient-Derived | #9 | ITK | TEC | 86% | 91% | 80% |
Patient-Derived | #10 | FRK | FRK | 84% | 78% | 91% |
All | #1 | DDR2 | DDR | 100% | 100% | - |
All | #2 | TXK | TEC | 96% | 96% | 97% |
All | #3 | PTK7 | PTK7 | 96% | - | 96% |
All | #4 | LYN | SRC | 96% | 91% | 100% |
All | #5 | LCK | SRC | 95% | 91% | 99% |
All | #6 | TEC | TEC | 93% | 96% | 91% |
All | #7 | BLK | SRC | 90% | 91% | 88% |
All | #8 | SRMS | SRC | 88% | 91% | 84% |
All | #9 | FRK | FRK | 87% | 83% | 92% |
All | #10 | PDGFRA | PDGFR | 84% | 87% | 81% |