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. 2020 Nov 17;12(11):3407. doi: 10.3390/cancers12113407

Figure 4.

Figure 4

Sting loss affects immunogenic tumor remodeling according to NanoString RNA profiling. (A) The panel reports the heat map for representative differentially regulated genes between Sting knockout untreated (KO) and treated (KO T) tumors. Values were normalized by nSolver software and filtered according to p-value (<0.05) and fold (±1.5). (B) The genes were grouped in 11 immune-relevant categories to obtain an overview of the gained trend from NanoString analysis.