Table 3.
Five-year progression-free survival (PFS) and five-year overall survival (OS) of patients stratified by the presence of genetic and cytogenetic alterations.
| Number of Patients | Five-Year PFS Probability * | p | Five-Year OS Probability * |
p | |
|---|---|---|---|---|---|
| Driver Mutations | Yes = 24 | 0.5 (0.1) | 0.001 | 0.79 (0.08) | ns |
| No = 31 | 0.77 (0.08) | 0.87 (0.06) | |||
| Unfavorable Mutations | Yes = 11 | 0.18 (0.12) | <0.001 | 0.73 (0.13) | 0.01 |
| No = 44 | 0.77 (0.06) | 0.86 (0.05) | |||
| Number of Mutations | One = 15 | 0.71 (0.07) | 0.001 | 0.85 (0.05) | 0.03 |
| 2 or more = 9 | 0.33 (0.16) | 0.78 (0.14) | |||
| SCNA | Unfavorable = 5 | 0.2 (0.18) | 0.002 | 0.4 (0.22) | <0.001 |
| None = 20 | 0.55 (0.11) | 0.8 (0.09) | |||
| Favorable = 30 | 0.8 (0.07) | 0.93 (0.05) | |||
| Prognostic Groups | Unfavorable = 12 | 0.17 (0.11) | 0.03 | 0.67 (0.14) | 0.02 |
| None = 12 | 0.62 (0.13) | 0.77 (0.11) | |||
| Favorable = 31 | 0.86 (0.007) | 0.93 (0.05) |
* Percentage (standard deviation); ns: Non-significant.