Figure 5.

IPA regulatory network with the highest consistency score (6.414) in ASCs isolated from three patients (after RNA pooling) and stimulated with the PDGF2 peptide (1 μg/mL) compared with parallel controls untreated with PDGF2. The consistency score is a measurement used to describe the relationship among the observed expression profile and upstream and downstream regulatory effects. The values below the molecules correspond to log2-fold changes in expression and p-value. Negative and positive values indicate a decrease and an increase in expression, respectively. In the bottom panel, the arrow shows the activation or inhibition of a downstream effect. ASCs, adipose-derived stem cells; IPA, Ingenuity Pathway Analysis.