Table 4. Fractional inhibitory concentration indexes (FICI) of human defensins in combination with rifampicin (RIF) against S. aureus isolates.
| S. aureus isolates | FICI | ||
|---|---|---|---|
| HNP-1 + RIF | hBD-1 + RIF | hBD-3 + RIF | |
| SA-1 | 0.5 | 1.5 | 0.5 |
| SA-2 | 0.5 | 1 | 0.5 |
| SA-3 | 0.375 | 0.75 | 0.375 |
| SA-4 | 0.75 | 0.75 | 0.875 |
| SA-5 | 0.375 | 0.5 | 0.5 |
| SA-6 | 0.625 | 1.5 | 0.5 |
| SA-7 | 0.5 | 1.25 | 0.5 |
| SA-8 | 0.5 | 0.75 | 0.375 |
| SA-9* | 0.375 | 0.75 | 0.625 |
| SA-10* | 0.5 | 0.625 | 0.5 |
| SA-11* | 0.375 | 1.25 | 0.3125 |
| SA-12* | 0.15625 | 0.75 | 0.375 |
| SA-13* | 0.5 | 0.5 | 0.5 |
| SA-14* | 0.5 | 0.5 | 0.375 |
| SA-15* | 0.3125 | 0.75 | 0.25 |
| SA-16* | 0.28125 | 0.625 | 0.5 |
| SA-17* | 0.375 | 0.75 | 0.375 |
| SA-18* | 0.5 | 1.25 | 0.5 |
| SA-19* | 0.625 | 1.0625 | 0.375 |
| SA-20* | 0.265625 | 1.125 | 0.375 |
| SA-21* | 0.375 | 1.5 | 0.75 |
| SA-22* | 0.25 | 1.25 | 0.5 |
| SA-23* | 0.5 | 1.25 | 0.5 |
| SA-24* | 0.5 | 0.625 | 0.375 |
| SA-25* | 0.5 | 1.125 | 0.375 |
| SA-26* | 0.3125 | 1.5 | 0.375 |
| SA-27* | 0.375 | 0.75 | 0.5 |
Notes:
*
MRSA.
FICI ≤ 0.5—synergistic effect; 0.5 < FICI < 4—no interaction; FICI > 4—antagonism.