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. 2020 Nov 18;12(11):3416. doi: 10.3390/cancers12113416

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Analysis of apoptosis and proliferation. (A) Apoptotic and mitotic indices have been measured in in vitro-cultured teratoma HE slides as total number of apoptotic or mitotic cells in differentiated and undifferentiated teratoma tissue. Values represented are means with 95% CI. (B) IHC analysis of apoptosis and proliferation in in vitro-treated teratoma. Proliferation has been analyzed based on Ki-67 protein expression, while apoptosis by caspase-3 expression. Values represented are means with 95% CI.