Skip to main content
. 2020 Nov 18;21(22):8696. doi: 10.3390/ijms21228696

Table 5.

Antibacterial activity of Bi(III) carboxylate complexes against Helicobacter pylori strain 26695.

Compound Representation of Bi(III) Coordination Chromophore MIC µg mL−1 (µM) Ref.
Pyridinedicarboxylic acid
[Bi2(2,3pydc)2(2,3pydcH)2(H2O)]n (1) graphic file with name ijms-21-08696-i001.jpg {BiO7N2} 15.0 (13.7) This work
{(Et3NH)2[Bi(2,3pydc)(2,3pydcH)Cl2]}n (2) graphic file with name ijms-21-08696-i002.jpg {BiO4N2Cl2} 30.0 (36.8)
BSS 12.5 (34.5)
Indolecarboxylic acid
[Bi(IAA)3] Inline graphic
[Bi(IAA)3]
{BiO6} 6.25 (8.54) [67]
[Bi(IPA)3] {BiO6} 6.25 (8.07)
[Bi(IBA)3] {BiO6} 6.25 (7.66)
[Bi(MICA)3] {BiO6} 6.25 (8.54)
[Bi(IGA)3] {BiO6} 6.25 (8.08)
BSS 12.5 (34.5)
Acetylsalicylic acid
[Bi(asp)3] Inline graphic
[Bi(asp)3]
{BiO8} 6.25 (8.37) [70]
[KBi(asp)4] {BiO9} 6.25 (6.48)
NSAIDs
[Bi(L1)3·H2O] Inline graphic
[Bi(Ketoprofen)3·H2O]
{BiO6} ≥6.25 (6.35) [68]
≥6.25 (4.85)
[Bi(L2)3] {BiO6} ≥6.25 (7.01)
≥6.25 (7.58)
≥6.25 (6.47)
≥6.25 (8.67)
≥6.25 (6.75)
≥6.25 (6.55)
≥6.25 (6.33)
≥6.25 (5.97)
BSS ≥12.5 (34.5)

2,3pydcH2—pyridine-2,3-dicarboxylic acid; Et3N—triethylamine; BSS—bismuth subsalicylate; IAA-H—2-(1H-indol-3-yl)acetic acid, IPA-H—3-(1H-indol-3-yl)propanoic acid, IBA-H—4-(1H-indol-3-yl))butanoic acid, IGA-H—2-(1H-indol-3-yl))-2-oxoacetic acid, MICA-H—1-methyl-1H-indole-3-carboxylic acid; aspH—acetylsalicylic acid; NSAIDs: L1: Ketoprofen, Sulindac; L2: Naproxen, Ibuprofen, Fenbufen, 5-Chlorosalicylic acid, Mefenamic acid, Diflunisal, Tolfenamic acid, Flufenamic acid.