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. 2020 Nov 18;12(11):3410. doi: 10.3390/cancers12113410

Figure 1.

Figure 1

HSP70 and eIF4G expression are significantly higher in hepatocellular carcinoma (HCC) tumor specimens. (A) Representative pictures of H&E and IF staining. Magnification, 20×; Scale bar, 50μm. (B) The protein levels of HSP70 and eIF4G in HCC tumor specimens were significantly higher than those of adjacent non-tumor specimens. (C) Heatmap showing the relative protein expression of eIF4A, eIF4E, eIF4G, 4EBP1, and HSP70 in all HCC patients tissue samples based on IF staining results. (D) Heatmap showing the average relative protein expression of eIF4A, eIF4E, eIF4G, 4EBP1, and HSP70 in all patients in each TNM stage. (E,F) Protein expression of HSP70 and eIF4G in HCC patients displayed according to the TNM stage. (G,H) The scatter plot of correlation between the AFP level and the protein expression of HSP70 and eIF4G. * p < 0.05, *** p < 0.001 compared with the adjacent non-tumor groups.