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Relative IC50 comparison among the bladder cancer cell lines used in the studies.
| Cell Line | Kras/Hras/Nras Status | IC50 * |
|---|---|---|
| HT1376 | Wild type | >200 nM |
| T-24 | Hras mutation | ~13 nM |
| UMUC3 | Kras mutation | ~3 nM |
| RT112 | Wild type | >160 nM |
| 253 J B-V | Wild type | >110 nM |
| TCCSUP (HTB-5) | Wild type | >160 nM |
| SNU-C2B (CRC) | Kras mutation | ~2.7 nM |
| HCT116 (CRC). | Kras mutation | ~0.51 nM |
* IC50 is the 72 h FL118 treatment.
