Table 2.
Changes in clinical variables (mean ± SD) over the 6-month experimental period (gingival crevicular fluid (GCF) sampling sites).
| Variables | Group | Moderate Pocket Sites (4–5 mm) |
Deep Pocket Sites (≥6 mm) |
||
|---|---|---|---|---|---|
| Baseline | 6 Months | Baseline | 6 Months | ||
| PI | Stage B | 85.0 ± 23.5 | 10.0 ± 20.5 *** | 92.5 ± 18.3 | 25.0 ± 30.3 *** |
| Stage C | 77.5 ± 25.5 ¶ | 15.0 ± 28.6 *** | 95.0 ± 15.4 | 20.0 ± 29.9 *** | |
| Difference between groups | NS | NS | NS | NS | |
| GI | Stage B | 2.0 ± 0.5 ¶ | 0.6 ± 0.5 *** | 2.6 ± 0.5 | 0.9 ± 0.8 *** |
| Stage C | 1.8 ± 0.4 ¶ | 0.4 ± 0.6 *** | 2.4 ± 0.4 | 0.8 ± 0.7 *** | |
| Difference between groups | NS | NS | NS | NS | |
| PD (mm) | Stage B | 4.7 ± 0.5 | 3.0 ± 1.0 *** | 8.2 ± 1.4 | 4.5 ± 0.9 ***,§ |
| Stage C | 4.8 ± 0.4 | 3.2 ± 0.6 *** | 8.9 ± 1.7 | 4.9 ± 1.0 ***,§ | |
| Difference between groups | NS | NS | NS | NS | |
| CAL (mm) | Stage B | 5.8 ± 1.4 | 4.5 ± 1.8 ** | 9.3 ± 2.1 | 6.4 ± 2.1 **,§ |
| Stage C | 5.3 ± 0.7 | 4.1 ± 1.1 *** | 9.6 ± 1.9 | 6.6 ± 1.4 ***,§ | |
| Difference between groups | NS | NS | NS | NS | |
| GCF (µL) | Stage B | 0.56 ± 0.36 | 0.22 ± 0.15 ** | 1.09 ± 0.25 § | 0.45 ± 0.21 ***,§ |
| Stage C | 0.59 ± 0.39 | 0.27 ± 0.20 * | 1.13 ± 0.33 § | 0.54 ± 0.31 **,¶ | |
| Difference between groups | NS | NS | NS | NS | |
SD: standard deviation; GCF: gingival crevicular fluid; PI: presence of plaque; GI: gingival index; PD: probing depth; CAL: clinical attachment level; NS: difference between groups is not statistically significant (p > 0.05); * p < 0.05 versus baseline; ** p < 0.01 versus baseline. *** p < 0.001 versus baseline; ¶ p < 0.01 versus moderate pocket sites; § p < 0.001 versus moderate pocket sites.