HNSCC	Head and neck squamous cell carcinoma
AUC	Area under the receiver operating curve
HPV	Human papillomavirus
AN	Adjacent normal
ORF	Open reading frame
OUT	Operational taxonomic unit
ASV	amplicon sequence variant
PERMANOVA	Permutational multivariate analysis of variance
MWU	Mann–Whitney Wilcoxon rank sum test
WSR	Wilcoxon signed rank test
KW	Kruskal–Wallis test
Tukey HSD	Tukey’s honest significant difference
ROC	Receiver operating characteristic
KEGG	Kyoto Encyclopedia of Genes and Genomes
KO	Kyoto Encyclopedia of Genes and Genomes Orthology
FFPE	Formalin-fixed paraffin-embedded
DMRs	Differentially methylated regions
TCGA	The cancer genome atlas
HR	High risk
PCoA	Principal coordinate analysis
LefSe	Linear discriminant analysis effect size
LDA	Linear discriminant analysis
PICRUSt2	Phylogenetic Investigation of Communities by Reconstruction of Unobserved States 2
DSS	Disease specific survival
DFS	Disease free survival
ISH	In situ hybridization
Glm nb	generalized linear regression model test
TSG	tumor suppressor gene
LXN	Latexin
qPCR	Quantitative PCR
F-Low	Fusobacterium-low
F-High	Fusobacterium-high