Figure 1.

Patient 1, aged 51, diagnosed with systemic sclerosis (SSc) 6 years before the analysis. The image (A) shows mask-like facial appearance with characteristic pinched nose, radial furrowing around the mouth, lip thinning and retraction, microstomia, and one single teleangiectasia. (B) Nailfold videocapillaroscopy of active SSc pattern in the patient 1 with early desorganization of microvascular architecture; loss of capillaries with lowered density to six capillaries in linear mm; presence of dilated capillary (>20 μm) with abnormal shape and ramification. The capillaries were marked with arrows. Images of right (C,E,G) and left (D,F,H) eye fundus of a patient 1, Data presented as fluorescein angiography (FA) versus optical coherence tomography (OCT). Color photo (C) and FA results (E) of the right eye fundus: in the recirculation phase, hyperfluorescence foci by a leakage from the microaneurysms can be observed (arrow). Color photo of the left eye fundus (D): vasodilation of the optical disc (a), intraretinal hemorrhages (b), macular edema (c), sectional narrowing of retinal vessels (d) may be noted. Results of fluorescein angiography of the left eye (F): diffuse macular leakage (a), foci of fluorescence blockade (b), laser photocoagulation scars (c) can be seen. Sclerodermic macular edema in right (G) and left eye (H) OCT examination.