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. 2020 Nov 18;21(22):8710. doi: 10.3390/ijms21228710

Table 3.

A2BAR ligands with antinociceptive effects in preclinical models of pain.

Ligand Pharmacological Behavior Pain Model Species Route of Administration
BAY606583 agonist CCI-induced mechanical allodynia mouse i.t. [96]
PSB-10 antagonist formalin test mouse i.p. [105]
PSB-36 antagonist formalin test mouse i.p. [105]
PSB-1115 antagonist formalin test mouse i.p. [105]

CCI (chronic constriction injury); i.t. (intrathecal); i.p. (intraperitoneal).