Table 1.
Baseline Demographic and Clinical Characteristics
| Total cohort (N = 527), n (%) | Died within one-year of transplant (N = 127), n (%) | |
|---|---|---|
| Age, years (median, range) | 65.5 (60–78.4) | 65.5 (60–75.2) |
| Gender | ||
| Female | 213 (40) | 55 (43) |
| Male | 314 (60) | 72 (57) |
| Race/ethnicity | ||
| Caucasian | 484 (92) | 114 (90) |
| Non-Caucasian | 43 (8) | 13 (10) |
| Marital status | ||
| Married/partnered | 430 (82) | 106 (83) |
| Single/divorced | 97 (18) | 21 (17) |
| Diagnosis | ||
| Myeloid | 366 (69) | 88 (69) |
| Lymphoid | 161 (31) | 39 (31) |
| Comorbidity | ||
| HCT-CI 0–2 | 240 (46) | 43 (34) |
| HCT-CI ≥3 | 287 (54) | 84 (66) |
| KPS at transplant | ||
| <90 | 247 (47) | 54 (43) |
| ≥90 | 273 (53) | 72 (57) |
| Missing | 7 | 1 |
| Disease risk index | ||
| Low/intermediate | 383 (73) | 80 (63) |
| High/very high | 144 (27) | 47 (37) |
| Conditioning intensity | ||
| RIC/NMA | 218 (41) | 51 (40) |
| Myeloablative | 309 (59) | 76 (60) |
| Donor | ||
| Matched | 402 (76) | 87 (69) |
| Alternative | 125 (24) | 40 (31) |
| ADL/IADL | ||
| Normal | 368 (87) | 80 (78) |
| Impaired | 55 (13) | 23 (22) |
| Missing | 104 | 24 |
| PIM user | ||
| No | 297 (56) | 60 (47) |
| Yes | 230 (44) | 67 (53) |
| Depression | ||
| No | 439 (83) | 106 (83) |
| Yes | 88 (17) | 21 (17) |
| Prior fall | ||
| No | 431 (82) | 103 (81) |
| Yes | 96 (18) | 24 (19) |
| Weight loss | ||
| No | 439 (83) | 99 (78) |
| Yes | 88 (17) | 28 (22) |
ADL, activities of daily living; HCT-CI, hematopoietic cell transplantation-comorbidity index; IADL, instrumental activities of daily living; KPS, Karnofsky Performance Status; PIM, potentially inappropriate medication; RIC/NMA, reduced-intensity/nonmyeloablative conditioning.