Table 5.

Relationship between best overall response and survival.

			Overall Survival
									Crude
	N = 88	(%)	median (months)	(95% CI)	1-year OS (%)	(95% CI)	2-year OS (%)	(95% CI)	HR	(95% CI)	p-value
CR/PR	16	(18)	NR		94	(63–99)	94	(63–99)	0.02	(0.003–0.15)	<0.001
SD	26	(30)	11.1	(8.6–20.7)	46	(27–64)	27	(12–45)	0.37	(0.21–0.65)	0.001
PD	46	(52)	6.4	(3.3–9.0)	17	(8–30)	0	(NA-NA)	1 (reference)
			Progression-Free Survival
									Crude
	N = 88	(%)	median (months)	(95% CI)	1-year PFS (%)	(95% CI)	2-year PFS (%)	(95% CI)	HR	(95% CI)	p-value
CR/PR	16	(18)	NR	(22.1-NA)	88	(59–97)	78	(44–93)	0.02	(0.005–0.06)	<0.001
SD	26	(30)	7.0	(4.3–12.4)	34	(16–52)	17	(5–34)	0.10	(0.05–0.22)	<0.001
PD	46	(52)	1.5	(1.1–2.5)	NA	(NA-NA)	0	(NA-NA)	1 (reference)

Abbreviations: NA, not available; NR, not reached.