Skip to main content
. 2020 Nov 19;9(11):827. doi: 10.3390/antibiotics9110827

Table 1.

Summary of most important phage therapy trials.

Year Target Results Factors Responsible for Failure Reference
2016 E. coli/Proteus (children diarrhea) Lack of clinical efficacy of oral phages Insufficient phage coverage; too low E. coli titers; overgrowth of Streptococcus [3]
2017 P. aeruginosa/E.coli (burn infections) Trial was stopped because of insufficient efficacy Decreased titer of phage preparations [4]
2020 Staphylococcus
Streptococcus
E. coli
P. aeruginosa
Proteus
(urinary tract infections)
Success rates similar to placebo (bladder irrigation) Reduction of the bacterial load caused by bladder irrigation with placebo comparable with the effect of phage preparations [1]