Table 3.
Correlations between gut microbiota composition and serum levels of TNF-alpha, IL-10, zonulin and FOXP3 mRNA expression in the study groups.
| pSS | Healthy Controls | pSS | Healthy Controls | pSS | Healthy Controls | pSS | Healthy Controls | |
|---|---|---|---|---|---|---|---|---|
| TNF-Alpha | IL-10 | Zonulin | FOXP3 mRNA Expression | |||||
| Ruminococcus | −0.496 (p = 0.031) | 0.563 (p = 0.035) | 0.494 (p = 0.032) | −0.496 (p = 0.031) | −0.665 (p = 0.005) | 0.573 (p = 0.034) | ||
| Butyciromonas | −0.560 (p = 0.033) | 0.525 (p = 0.021) | −0.542 (p = 0.027) | 0.598 (p = 0.043) | ||||
| Blautia | 0.516 (p = 0.024) | 0.576 (p = 0.005) | ||||||
| Roseburia | −0.458 (p = 0.048) | 0.501 (p = 0.042) | ||||||
| Prevotella copri | 0.645 (p = 0.003) | |||||||
| Clostridium | 0.550 (p = 0.025) | −0.651 (p = 0.033) | ||||||
| Bifidobacterium | −0.580 (p = 0.009) | −0.631 (p = 0.010) | −0.584 (p = 0.017) | |||||
| Bacteroides fragilis | −0.567 (p = 0.041) | 0.631 (p = 0.002) | 0.563 (p = 0.009) | |||||
| Faecalibacterium prausnitzii | 0.651 (p = 0.010) | 0.597 (p = 0.025) | −0.502 (p = 0.029) | |||||
| Parabacteroides distasonis | −0.559 (p = 0.009) | −0.700 (p = 0.035) | ||||||