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Model characterization and measures of basic parameters. (A) Bodyweight changes over time, (B) Total lung volume over time, assessed by MRI, and (C) right lung lobe weigh at termination (from Group II). (D) Fibrosis scoring evaluated by the modified Ashcroft score at day 28, 35, and 42 post-bleomycin challenge. Representative images of lung tissue sections stained by (E) H&E and (F) Sirius Red.
