Table 4.
Odds ratio (OR) and 95% confidence interval (CI) of the clinicopathological characteristics and MMP-11 rs738791 genotypic frequencies in 578 patients with prostate cancer.
| Variable | Genotypic Frequencies | |||
|---|---|---|---|---|
| rs738791 | CC (n = 272) | CT + TT (n = 306) | OR (95% CI) | p-Value |
| Pathologic Gleason grade group | ||||
| 1 + 2 + 3 | 233 (85.7%) | 250 (81.7%) | 1.00 | p = 0.199 |
| 4 + 5 | 39 (14.3%) | 56 (18.3%) | 1.338 (0.857–2.091) | |
| Clinical T stage | ||||
| 1 + 2 | 233 (85.7%) | 267 (87.3%) | 1.00 | p = 0.576 |
| 3 + 4 | 39 (14.3%) | 39 (12.7%) | 0.873 (0.541–1.407) | |
| Pathologic T stage | ||||
| 2 | 153 (56.3%) | 153 (50.0%) | 1.00 | p = 0.133 |
| 3 + 4 | 119 (43.8%) | 153 (50.0%) | 1.286 (0.926–1.785) | |
| Pathologic N stage | ||||
| N0 | 250 (91.9%) | 279 (91.2%) | 1.00 | p = 0.751 |
| N1 | 22 (8.1%) | 27 (8.8%) | 1.100 (0.611–1.980) | |
| Seminal vesicle invasion | ||||
| No | 216 (79.4%) | 235 (76.8%) | 1.00 | p = 0.449 |
| Yes | 56 (20.6%) | 71 (23.2%) | 1.165 (0.784–1.732) | |
| Perineural invasion | ||||
| No | 75 (27.6%) | 80 (26.1%) | 1.00 | p = 0.699 |
| Yes | 197 (72.4%) | 226 (73.9%) | 1.076 (0.744–1.555) | |
| Lymphovascular invasion | ||||
| No | 231 (84.9%) | 250 (81.7%) | 1.00 | p = 0.300 |
| Yes | 41 (15.1%) | 56 (18.3%) | 1.262 (0.812–1.961) | |
| D’Amico classification | ||||
| Low/Intermediate risk | 136 (50.0%) | 143 (46.7%) | 1.00 | p = 0.433 |
| High risk | 136 (50.0%) | 163 (53.3%) | 1.140 (0.822–1.581) | |
The ORs analyzed by their 95% CIs were estimated by logistic regression models.