Table 6.
Odds ratio (OR) and 95% confidence interval (CI) of the clinicopathological characteristics and MMP-11 rs738792 genotypic frequencies in 578 patients with prostate cancer.
| Variable | Genotypic Frequencies | |||
|---|---|---|---|---|
| rs738792 | TT (n = 263) | TC + CC (n = 315) | OR (95% CI) | p-Value |
| Pathologic Gleason grade group | ||||
| 1 + 2 + 3 | 220 (83.7%) | 263 (83.5%) | 1.00 | p = 0.959 |
| 4 + 5 | 43 (16.3%) | 52 (16.5%) | 1.012 (0.650–1.574) | |
| Clinical T stage | ||||
| 1 + 2 | 224 (85.2%) | 276 (87.6%) | 1.00 | p = 0.391 |
| 3 + 4 | 39 (14.8%) | 39 (12.4%) | 0.812 (0.503–1.308) | |
| Pathologic T stage | ||||
| 2 | 129 (49.0%) | 177 (56.2%) | 1.00 | p = 0.087 |
| 3 + 4 | 134 (51.0%) | 138 (43.8%) | 0.751 (0.540–1.043) | |
| Pathologic N stage | ||||
| N0 | 242 (92.0%) | 287 (91.1%) | 1.00 | p = 0.698 |
| N1 | 21 (8.0%) | 28 (8.9%) | 1.124 (0.623–2.030) | |
| Seminal vesicle invasion | ||||
| No | 220 (76.0%) | 251 (79.7%) | 1.00 | p = 0.293 |
| Yes | 63 (24.0%) | 64 (20.3%) | 0.809 (0.546–1.201) | |
| Perineural invasion | ||||
| No | 65 (24.7%) | 90 (28.6%) | 1.00 | p = 0.297 |
| Yes | 198 (75.3%) | 225 (71.4%) | 0.821 (0.566–1.190) | |
| Lymphovascular invasion | ||||
| No | 222 (84.4%) | 259 (82.2%) | 1.00 | p = 0.483 |
| Yes | 41 (15.6%) | 56 (17.8%) | 1.171 (0.753–1.820) | |
| D’Amico classification | ||||
| Low/Intermediate risk | 122 (46.4%) | 157 (49.8%) | 1.00 | p = 0.408 |
| High risk | 141 (53.6%) | 158 (50.2%) | 0.871 (0.627–1.209) | |
The ORs analyzed by their 95% CIs were estimated by logistic regression models.