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Nurse-like cells (NLCs), along with endothelial cells, fibroblasts and monocytes, secrete chemokines like CXCL9, CXCL10, CXCL11, which will bind the CXCR3 receptor expressed on the chronic lymphocytic leukemia (CLL) B cells and attract the cells into the tumor microenvironment (TME).
