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An EGFR-centric view of the involvement of EVs in the Hallmarks of Cancer [97], summarising the key findings for the role of EGFR+/Ligand+ EVs in the “achievement” of each. The central cartoon schematically depicts a sEV displaying EGFR, a full-length transmembrane EGFR family ligand, a tetraspanin marker and nucleotidic cargo. Findings are denoted by first author and year and colour-coded according to the role played by EGFR and/or its ligands in the biological outcome referenced.
