TABLE 1.
Demographic and clinical information
| Variables | Control | BiV (n = 7) | P value | TGA (n = 11) | P value | SV (n = 13) | P value |
|---|---|---|---|---|---|---|---|
| Demographic | |||||||
| Female sex | 5/13 (38%) | 3/7 (43%) | 1.00 | 1/11 (9%) | .17 | 4/13 (31%) | 1.00 |
| Gestational age, wk | 39.3 (38.9, 39.6) | 38.1 (37.7, 39.3) | .23 | 39.4 (39.0, 40.1) | .62 | 39.0 (38.3, 39.1) | .25 |
| Birth weight, kg | 3.4 (3.2, 3.5) | 2.8 (2.3, 3.6) | .16 | 3.2 (3.0, 3.6) | .50 | 3.2 (2.8, 3.4) | .11 |
| Surgical | |||||||
| Age at surgery, d | NA | 9 (5, 13) | NA | 4 (3, 6) | NA | 3 (3, 5) | NA |
| SaO2 at time of surgery, % | 99* (98, 100) | 96 (90, 100) | <.01 | 93 (87, 96) | <.01 | 98 (95, 98) | .02 |
| Lowest temperature (rectal) on CPB, °C | NA | 23.5 (21.6, 25.9) | NA | 23.7 (18.3, 27.7) | NA | 19.9 (18.0, 22.2) | NA |
| Duration of CPB, min | NA | 148 (141, 194) | NA | 178 (163, 198) | NA | 139 (131, 158) | NA |
| Crossclamp time, min | NA | 127 (107, 144) | NA | 115 (101, 126) | NA | 79 (61, 97) | NA |
| Circulatory arrest time, min | NA | 24 (10, 37) n = 4 | NA | 10 (9, 13) n = 7 | NA | 12 (8, 20) n = 13 | NA |
| RCP time, min | NA | 68 (38, 76) n = 3 | NA | 40 n = 1 | NA | 61 (47, 75) n = 13 | NA |
| Postoperative | |||||||
| Duration of postoperative intubation, d | NA | 4 (3, 6) | NA | 2 (2, 5) | NA | 7 (6, 8) | NA |
| Length of postoperative CICU stay, d | NA | 6 (5, 8) | NA | 6 (3, 12) | NA | 14 (11, 17) | NA |
| Length of hospital stay, d | NA | 29 (16, 33) | NA | 18 (12, 30) | NA | 38 (31, 48) | NA |
Categorical variable (sex) is presented as counts with percentages. Continuous variables are presented as medians and interquartile range. Note that P values correspond to comparisons between each CHD group (BiV, TGA, SV) and controls. BiV, Biventricular heart disease without transpostion of the great arteries; TGA, d-transposition of the great arteries; SV, single-ventricle heart disease; NA, not applicable; SaO2, arterial saturation; CPB, cardiopulmonary bypass; RCP, regional cerebral perfusion; CICU, cardiac intensive care unit.
*
At time of measurement in nursery.