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. 2020 Nov 24;13:3095–3106. doi: 10.2147/JPR.S281041

Table 2.

Comparison Between Postoperative Pain Intensity, Fentanyl Consumption Using Intravenous Patient-Controlled Analgesia (IV-PCA), and Rescue Analgesic Use in Patients with and without Basal Infusion of Fentanyl in IV-PCA Before and After Propensity Score Matching

Before Matching After Matching
Basal Group No Basal Group P-value Median Difference (95% CI) Basal Group No Basal Group P-value Median Difference (95% CI)
At 24h postoperatively
 Total numbers 560 757 539 539
 NRS at resting, 0–10 4 (2–6) 4 (2–6) 0.044 0 (0–1) 4 (2–6) 4 (2–6) 0.032 0 (0–1)
 Maximal NRS, 0–10 7 (5–8) 7 (5–8) 0.910 0 (0–0) 7 (5–8) 7 (5–8) 0.620 0 (0–0)
 IV fentanyl PCA use, mcg 604 (480–742) 460 (120–740) < 0.001 −126 (−180 – −90) 600 (480–743) 520 (160–760) < 0.001 −80 (−112 – −45)
 Rescue analgesics use during first 24 h postoperatively 333 (59.5) 456 (60.2) 0.821 319 (59.2) 316 (58.6) 0.901
 Number of rescue analgesics during first 24 h postoperatively 1 (0–2) 1 (0–2) 0.456 0 (0–0) 1 (0–2) 1 (0–1) 0.971 0 (0–0)
At 48h postoperatively
 Total numbers 352 419 338 300
 NRS at resting, 0–10 3 (1–4) 3 (1–4) 0.152 0 (0–1) 3 (1–4) 3 (1–4) 0.146 0 (0–1)
 Maximal NRS, 0–10 5 (4–7) 5 (3–7) 0.143 0 (−1 – 0) 5 (4–7) 5 (3–7) 0.347 0 (−1 – 0)
 IV fentanyl PCA use, mcga 1080 (768–1340) 600 (230–1140) < 0.001 −378 (−464 – −288) 1074 (757–1299) 720 (300–1200) < 0.001 −286 (−380 – −190)
 Rescue analgesics use during 24–48h postoperatively 57 (16.2) 92 (22.0) 0.054 87 (25.8) 86 (28.7) 0.420
 Number of rescue analgesics during 24–48h postoperatively 0 (0–0) 0 (0–0) 0.043 0 (0–0) 0 (0–0) 0 (0–0) 0.068 0 (0–0)

Notes: The values are presented as the median (interquartile range). aThis included 367 patients without basal infusion and 314 patients with basal infusion before matching. This included 266 patients without basal infusion and 303 patients with basal infusion after matching.

Abbreviations: NRS, numeric rating scale; PCA, patient-controlled analgesia.